Comorbid Insomnia and Sleep Apnea-Comorbid Insomnia and Sleep Apnea PPT

Comorbid Insomnia and Sleep Apnea PPT

Pdf Summary

COMISA, which stands for Combined Obstructive Sleep Apnea and Insomnia, is a condition that involves both sleep apnea and insomnia. It has major implications in the fields of Sleep Medicine and Dental Sleep Medicine. Insomnia is defined as persistent difficulty with sleep initiation, duration, consolidation, or quality, resulting in daytime impairment. Sleep apnea is characterized by repetitive episodes of upper airway obstruction during sleep, leading to reductions in blood oxygen saturation and brief arousals.<br /><br />The prevalence of COMISA is estimated to be around 16-18% in adults and up to 50% in sleep-related breathing disorders. It is more common in males before the age of 50, while females are more affected after the age of 50. Patients with COMISA often have a higher body mass index (BMI) and are more likely to smoke or have sedentary lifestyles.<br /><br />Research has shown that individuals with COMISA have a higher risk of developing cardiovascular and metabolic disorders. The combination of sleep apnea and insomnia leads to increased sympathetic activity, oxidative stress, inflammation, endothelial dysfunction, and hormonal disturbances, all of which contribute to the development of cardiometabolic risk factors. Individuals with COMISA also have higher rates of hypertension and diabetes.<br /><br />Treatment options for COMISA include mandibular advancement devices (MADs), continuous positive airway pressure (CPAP) therapy, and cognitive-behavioral therapy for insomnia (CBTi). MADs have shown success in improving sleep apnea and insomnia symptoms in COMISA patients. CBTi has also shown promise in improving sleep quality and reducing insomnia symptoms in COMISA patients.<br /><br />Overall, it is important to accurately diagnose and effectively manage COMISA in order to reduce the risk of cardiovascular and metabolic disorders. Future research should focus on developing personalized treatment approaches that target both the sleep apnea and insomnia components of COMISA.

Keywords

COMISA

Combined Obstructive Sleep Apnea and Insomnia

Sleep Medicine

Dental Sleep Medicine

insomnia

sleep apnea

prevalence

cardiometabolic risk factors

treatment options

personalized treatment approaches